At Roche, we believe it's urgent to deliver medical solutions right now - even as we develop innovations for the future. We are passionate about transforming patients' lives and we are fearless in both decision and action. And we believe that good business means a better world.
That is why we come to work each day. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.
In the Immunology Therapeutic Area, we are developing cutting edge therapies to treat inflammatory diseases. As a member of the Immunology Therapeutic Area, you will be part of an international group that includes scientists and clinicians that are developing immunologic medicines for the future.
We're currently looking for a creative, motivated and experienced biomarker expert scientist with strong expertise in biomarker development, immunology, and a proven track record in managing biomarker strategies in a drug discovery and early clinical development setting.
You are a go-to person for biomarker related activities, working closely with scientists, clinicians and project teams to develop biomarker plans for preclinical and clinical stage projects .
You lead and act as an individual contributor for multidisciplinary expert teams. You are assigned to preclinical portfolio projects as an expert guide for early biomarker deliverables with increasing responsibilities until assuming full accountability for the clinical biomarker strategy up to phase II clinical development.
You integrate input from technical experts to develop, implement and adjust state of the art analytical concepts recognizing the scientific and clinical basis, the validation status, and the statistical issues related to proposed biomarkers.
You are accountable for the interpretation of preclinical and clinical biomarker data and the communication to technical experts, senior leadership, governance bodies, clinical investigators, and health authorities.
You are responsible for biomarker-specific sections in internal and external documents (incl. study protocols, regulatory, reports, manuals, etc).
You integrate preclinical, clinical as well as real world data to develop project-specific patient enrichment options to increase the probability of clinical success.
You design and lead forward and reverse translational research studies and/or projects in collaboration with internal and external partners to support the preclinical and clinical immunology portfolio including prioritization and harmonization of biomarker platforms.
You stay up to date on novel biomarker modalities and technologies and you contribute to the overall strategy of our 'Biomarkers and Translational Technology' unit that consists of preclinical discovery scientists and clinical biomarker leaders.
You hold a PhD, MD or MD/PhD degree in a relevant scientific field, e.g. immunology, data science, pathology, or molecular biology with profound experience and exposure to discovery and development of biomarkers in immunology, either in a research or clinical setting.
You have at least 5 years of experience (beyond post-doctoral training) in drug development and translational research including discovery, development and utilization of biomarkers or biomarker-technologies either in an academic and/or industry setting, supported by a strong publication record or equivalent contributions.
You have previous experience supporting clinical studies as a biomarker study lead; including the creation and execution of the biomarker plan and the successful implementation of internal and external biomarker activities.
You have expertise in generating and interpreting data with different sample types and technologies to enable proof of biology, dose selection, and patient stratification across clinical programs.
You can work as an individual contributor and you are an experienced matrix leader and decision maker with strong presentation and leadership skills to influence and motivate teams.
Data analysis and integration are your strong points, a background in data science or biostatistics is a plus.
Knowledge of and exposure to regulatory, safety, and biosample operations is a plus.
A strong interest in understanding and developing skills in state of the art technologies is desirable.
A deep understanding of immunologic mechanisms underlying complex diseases is desirable.
As a team player you integrate easily into a pro-active and inspiring global organization. You are able to prioritize your work in order to focus on individual goals as well as on team deliverables. We can trust in your outstanding presentation and communication skills as well as in your ability to distill complex issues plus develop and clearly articulate solutions.
Are you ready to apply? We want someone who thinks beyond the job offered - someone who knows that this position can be a rare springboard to many other opportunities at Roche.
Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Who we are
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.
Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.
We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.
Roche is an Equal Opportunity Employer.